SOUTHERN MEDICAL JOURNAL, vol.99, no.3, pp.208-211, 2006 (SCI-Expanded)
Article / Article
SOUTHERN MEDICAL JOURNAL
Science Citation Index Expanded (SCI-EXPANDED), Scopus
gallbladder diseases, sildenafil citrate, ultrasonography, nitric oxide, LOWER ESOPHAGEAL SPHINCTER, NITRIC-OXIDE, HEALTHY-SUBJECTS, ORAL SILDENAFIL, MOTOR FUNCTION, PATHWAY
Dokuz Eylül University Affiliated:
Objective: Sildenafil stimulates the nitric oxide-cyclic guanosine monophosphate (NO-cGMP) pathway through inhibition of type 5 phosphodiesterase. NO-cGMP pathway causes smooth muscle relaxation. The aim of this study is to evaluate the effects of sildenafil on gallbladder motility.