Investigation of Cytomegalovirus in Intestinal Tissue in a Country With High CMV Seroprevalence.

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Hazir-Konya H., Avkan Oğuz V., Akarsu M., Sağol Ö., Sayiner A. A.

The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, vol.32, no.2, pp.123-132, 2021 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 32 Issue: 2
• Publication Date: 2021
• Doi Number: 10.5152/tjg.2021.191008
• Journal Name: The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE
• Page Numbers: pp.123-132
• Keywords: Cytomegalovirus, immunohistochemistry, polymerase chain reaction, intestinal tissue, INFLAMMATORY-BOWEL-DISEASE, ULCERATIVE-COLITIS, INFECTION, LOAD, PREVALENCE, BIOPSIES, THERAPY, ILEITIS
• Dokuz Eylül University Affiliated: Yes

Abstract

Background: In Turkey, cytomegalovirus (CMV) seropositivity has been reported to be high, between 85 and 100%. CMV has been responsible for disease exacerbation in inflammatory bowel disease (IBD). We aimed to evaluate the presence of CMV in intestinal tissue by immunohistochemical staining in IBD and non-IBD patient groups, in a country with high CMV seroprevalence.