Microcontroller Based Hodgkin-Huxley Model Neuron Simulation

Isler Y., KUNTALP M., Gonel G.

14th National Biomedical Engineering Meeting, İzmir, Türkiye, 20 - 22 Mayıs 2009, ss.389-392 identifier identifier

  • Yayın Türü: Bildiri / Tam Metin Bildiri
  • Cilt numarası:
  • Doi Numarası: 10.1109/biyomut.2009.5130348
  • Basıldığı Şehir: İzmir
  • Basıldığı Ülke: Türkiye
  • Sayfa Sayıları: ss.389-392
  • Anahtar Kelimeler: Simulation, Neuronal Modeling, Ionic Channels, Excitable Membranes, COMPUTER SOFTWARE, MICROSOFT EXCEL, TEMPERATURE
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

In this paper, new microcontroller based hardware for simulation of neurons is introduced. Excitable membranes with voltage-gated ionic channels can be modeled by using the hardware and current-clamp experiments can be simulated. The hardware allows user to supply the analog current to be injected to the model. First-order differential equations used to define dynamics of the gate and membrane potential are solved using forward Euler method of integration. Output of the simulation can be seen as analog values both on the computer screen via serial port and on the LCD display or expansion port of the designed board.