The Relationship Between Apoptotic Activity and Prognostic Factors in Neuroblastomas

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Ekmekci S., Olgun N., ÖZER E.

TURKISH JOURNAL OF PATHOLOGY, cilt.32, sa.2, ss.99-104, 2016 (ESCI) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 32 Sayı: 2
  • Basım Tarihi: 2016
  • Doi Numarası: 10.5146/tjpath.2015.01348
  • Dergi Adı: TURKISH JOURNAL OF PATHOLOGY
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.99-104
  • Anahtar Kelimeler: Apoptosis, Bcl-2, Neuroblastoma, Prognosis, PATHOLOGY CLASSIFICATION, TELOMERASE ACTIVITY, EXPRESSION, BCL-2, TUMORS, DEATH, GENE, DNA
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Objective: Prognostic parameters in determining risk groups for treatment in neuroblastoma are cellular differentiation, mitosis karyorrhexis index (MKI), N-myc amplification and age. However, additional prognosticators are still needed because patients can show unpredictable biological behavior. We aimed to study the prognostic significance of apoptotic activity in neuroblastomas.