The Relationship Between Apoptotic Activity and Prognostic Factors in Neuroblastomas

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Ekmekci S., Olgun N., ÖZER E.

TURKISH JOURNAL OF PATHOLOGY, vol.32, no.2, pp.99-104, 2016 (ESCI, Scopus, TRDizin) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 32 Issue: 2
  • Publication Date: 2016
  • Doi Number: 10.5146/tjpath.2015.01348
  • Journal Name: TURKISH JOURNAL OF PATHOLOGY
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.99-104
  • Keywords: Apoptosis, Bcl-2, Neuroblastoma, Prognosis
  • Open Archive Collection: AVESIS Open Access Collection
  • Dokuz Eylül University Affiliated: Yes

Abstract

Objective: Prognostic parameters in determining risk groups for treatment in neuroblastoma are cellular differentiation, mitosis karyorrhexis index (MKI), N-myc amplification and age. However, additional prognosticators are still needed because patients can show unpredictable biological behavior. We aimed to study the prognostic significance of apoptotic activity in neuroblastomas.