Atıf İçin Kopyala
Isik S., Karaman M., Micili S., Caglayan-Sozmen S., BAĞRIYANIK H. A., Arikan-Ayyildiz Z., ...Daha Fazla
Allergologia et immunopathologia, cilt.45, sa.4, ss.339-349, 2017 (SCI-Expanded)
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Yayın Türü:
Makale / Tam Makale
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Cilt numarası:
45
Sayı:
4
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Basım Tarihi:
2017
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Doi Numarası:
10.1016/j.aller.2016.12.003
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Dergi Adı:
Allergologia et immunopathologia
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Derginin Tarandığı İndeksler:
Science Citation Index Expanded (SCI-EXPANDED), Scopus
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Sayfa Sayıları:
ss.339-349
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Anahtar Kelimeler:
Asthma, Airway remodelling, Apoptosis, Ursodeoxycholic acid, Murine model, Th2, PRIMARY BILIARY-CIRRHOSIS, CHENODEOXYCHOLIC ACID, INFLAMMATION, EXPRESSION, EFFICACY, TRIAL, MECHANISMS, GALLSTONES, DISEASES, INJURY
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Dokuz Eylül Üniversitesi Adresli:
Evet
Özet
Background and aims: In previous studies, anti-inflammatory, anti-apoptotic and immunomodulatory effects of ursodeoxycholic acid (UDCA) on liver diseases have been shown. In this study, we aimed to investigate the effects of UDCA on airway remodelling, epithelial apoptosis, and T Helper (Th)-2 derived cytokine levels in a murine model of chronic asthma.