Comparative in vitro activity of plazomicin and older aminoglyosides against Enterobacterales isolates; prevalence of aminoglycoside modifying enzymes and 16S rRNA methyltransferases

Gur, Deniz; HASDEMİR GÖKBOĞA, MÜNEVVER; ÇAKAR, ASLI; Cavusoglu, Iffet; Celik, Tugce; AKSU, MEHMET; SANCAK, BANU; ALTUN, BELGİN; Soyletir, Guner; ÜLGER, NURVER; Kararuna, Onur; KARAHAN, ZEYNEP; EVREN, EBRU; Bakici, Zahir; ÇELİK, CEM; AKPOLAT, NEZAHAT; Gulay, Zeynep; Sari, Ayse; Aydemir, Sohret; ÇİLLİ, FATMA; KILIÇ, HÜSEYİN; PARKAN, ÖMÜR; ZER, YASEMİN; Buyuktas, Ayse; Koksal, Fauna; AYDIN, FARUK; ÖZKAYA, ESRA; BİRİNCİ, ASUMAN; ÇAYCI, YELİZ; Tuncer, Inci

doi:10.1016/j.diagmicrobio.2020.115092

Comparative in vitro activity of plazomicin and older aminoglyosides against Enterobacterales isolates; prevalence of aminoglycoside modifying enzymes and 16S rRNA methyltransferases

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Gur D., HASDEMİR GÖKBOĞA M. U., ÇAKAR A., Cavusoglu I., Celik T., AKSU M. B., ...More

DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE, vol.97, no.4, 2020 (SCI-Expanded)

Publication Type: Article / Article
Volume: 97 Issue: 4
Publication Date: 2020
Doi Number: 10.1016/j.diagmicrobio.2020.115092
Journal Name: DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Aquatic Science & Fisheries Abstracts (ASFA), BIOSIS, CAB Abstracts, EMBASE, Environment Index, MEDLINE, Veterinary Science Database
Keywords: Klebsiella, E. coli, armA, NDM-1, Serratia, 16S rRNA methyltransferase, Aminoglycoside resistance, Plazomicin, Aminoglycoside modifying enzyme, rmtB, rmtA, rmtE, rmtF, Enterobacter, OXA-48, rmtC, RESISTANCE MECHANISMS, ESCHERICHIA-COLI, KLEBSIELLA-PNEUMONIAE, CARBAPENEMASE, EMERGENCE, STRAINS
Dokuz Eylül University Affiliated: Yes

Abstract

Comparative in vitro activity of plazomicin and 4 older aminoglycosides was evaluated with broth microdilution in 714 blood isolates from 14 hospitals in Turkey.