A sensitive determination of dopamine in the presence of ascorbic acid using a nafion-coated clinoptilolite-modified carbon paste electrode

Alpat Ş., Kılınç Alpat S., Telefoncu A.

ANALYTICAL AND BIOANALYTICAL CHEMISTRY, cilt.383, sa.4, ss.695-700, 2005 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 383 Sayı: 4
  • Basım Tarihi: 2005
  • Doi Numarası: 10.1007/s00216-005-0037-2
  • Dergi Adı: ANALYTICAL AND BIOANALYTICAL CHEMISTRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.695-700
  • Anahtar Kelimeler: dopamine, nafion, clinoptilolite, carbon paste electrode, DPASV, ZEOLITE-MODIFIED ELECTRODES, AMPEROMETRIC DETERMINATION, VOLTAMMETRIC DETERMINATION, SELECTIVE DETECTION, ELECTROCATALYTIC OXIDATION, POLYPHENOL OXIDASE, URIC-ACID, BIOSENSOR, SEROTONIN, SENSOR
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

A selective dopamine determination using a nafion-coated clinoptilolite-modified carbon paste electrode in the presence of ascorbic acid was studied. Both cyclic voltammetry (CV) and differential pulse anodic stripping voltammetry (DPASV) were used for measurements of dopamine. To improve the selectivity of the clinoptilolite-modified carbon paste electrode in presence of a high concentration of ascorbic acid, the electrode surface was coated with nafion membrane. Experimental parameters affecting the determination of dopamine, including the clinoptilolite ratio, nafion membrane thickness, preconcentration time, preconcentration solution pH, stripping solution pH and interferences are discussed. The developed sensor has a wide linear range, a low detection limit, and good stability and reproducibility. The sensor offers a good alternative to existing analytical methods for dopamine, permits a relatively short analysis time, and is simple, selective and inexpensive.