Evaluation of Pneumococcal PCR and Urinary Antigen Detection in Children
CLINICAL LABORATORY, vol.59, no.11-12, pp.1409-1411, 2013 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 59 Issue: 11-12
- Publication Date: 2013
- Doi Number: 10.7754/clin.lab.2013.121206
- Journal Name: CLINICAL LABORATORY
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.1409-1411
- Keywords: pneumococcal antigen test, S. Pneumoniae, child
- Dokuz Eylül University Affiliated: No
Abstract
Background: The rapid detection of Streptococcus pneumoniae could assist in the management of pneumococcal infections. The Binax NOW S. pneumoniae test is a rapid immunochromatographic test for this purpose. Methods: Multiplex PCR in parapneumonic pleural effusion fluid (PPEF) and cerebrospinal fluid (CSF) with Binax NOW urinary pneumococcal antigen test (PAT) from 80 children was compared in this study. Results: PAT had a sensitivity of 36.4%, specificity of 97.3%, in CSF. PAT had a sensitivity of 50%, specificity of 81% for parapneumonic pleural effusion fluid. Conclusions: When rapid management of a serious infection is needed the Binax NOW test could be a reliable method for the exclusion of S. pneumoniae infection.