Vestibular impairment in chronic inflammatory demyelinating polyneuropathy


AKDAL HALMAGYI G., Tanriverdizade T., Sengun I., BADEMKIRAN F., Kocoglu K., YÜCEYAR A. N., ...More

JOURNAL OF NEUROLOGY, vol.265, no.2, pp.381-387, 2018 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 265 Issue: 2
  • Publication Date: 2018
  • Doi Number: 10.1007/s00415-017-8712-8
  • Journal Name: JOURNAL OF NEUROLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.381-387
  • Keywords: CIDP, Polyneuropathy, Vestibular, BALANCE, RELIABILITY
  • Dokuz Eylül University Affiliated: Yes

Abstract

Chronic inflammatory demyelinating polyneuropathy (CIDP) is a common, treatable, autoimmune peripheral neuropathy considered to produce imbalance by weakness and proprioceptive impairment rather than vestibular impairment. We measured semicircular canal vestibular function in 21 CIDP patients (15M/6F) by the video head impulse test and postural stability with a battery comprising the modified Clinical Test of Sensory Integration and Balance, the Berg Balance Scale, the Dynamic Gait Index, the Fall Efficiency Scale, and the International Cooperative Ataxia Rating Scale. Of the 21 patients, 16 had vestibular impairment, ranging from mild-affecting just a single semicircular canal, to severe-affecting all 6 canals. Although the severity of the vestibular impairment did not correlate either with the severity of the postural imbalance or of the peripheral neuropathy, our data show that vestibular impairment is an additional challenge to balance that some CIDP patients will face.