Correlation between serum YKL-40 (Chitinase-3-like protein 1) level and proteinuria in renal transplant recipients


Tatar E., Gungor O., ÇELTİK A., Sisman A., Yaprak M., AŞCI G., ...More

ANNALS OF TRANSPLANTATION, vol.18, pp.95-100, 2013 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 18
  • Publication Date: 2013
  • Doi Number: 10.12659/aot.883844
  • Journal Name: ANNALS OF TRANSPLANTATION
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.95-100
  • Keywords: YKL-40, proteinuria, C-reactive protein, endothelial dysfunction, renal transplantation, ENDOTHELIAL DYSFUNCTION, CARDIOVASCULAR-DISEASE, PREDICT MORTALITY, PATIENT SURVIVAL, MARKER, INFLAMMATION, BIOMARKER, CHI3L1
  • Dokuz Eylül University Affiliated: Yes

Abstract

Background: YKL-40 (chitinase-3-like protein 1) is a novel inflammation and endothelial dysfunction biomarker. Although YKL-40 is associated with albuminuria and predicts cardiovascular morbidity and mortality in a non-uremic population, it's status is not known in renal transplant recipients. The aim of this study was to investigate plausible links between serum YKL-40 and proteinuria.