Physical activity in women with subclinical hypothyroidism


Tanriverdi A., ÖZCAN KAHRAMAN B., Ozsoy I., Bayraktar F., Saydam B. O., Acar S., ...More

JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION, vol.42, no.7, pp.779-785, 2019 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 42 Issue: 7
  • Publication Date: 2019
  • Doi Number: 10.1007/s40618-018-0981-2
  • Journal Name: JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.779-785
  • Keywords: Subclinical hypothyroidism, Physical activity, Arterial stiffness, Six-minute walk test, Women, PULSE-WAVE VELOCITY, ALL-CAUSE MORTALITY, CARDIOVASCULAR EVENTS, ARTERIAL STIFFNESS, EXERCISE TOLERANCE, THYROID-DISEASE, HEART-DISEASE, RELIABILITY, RISK, REPLACEMENT
  • Dokuz Eylül University Affiliated: Yes

Abstract

PurposePhysical activity is associated with many health-related benefits. However, there is a shift towards inactive lifestyles around the world. Subclinical hypothyroidism (SCH) may have adverse effects similar to hypothyroidism. The presence of symptoms and reduced physical performance in SCH may contribute to an inactive lifestyle. Therefore, the present study aimed to compare physical activity levels (PALs) between women with subclinical hypothyroidism and healthy controls.MethodsThirty-two women with newly diagnosed SCH and 28 healthy women were enrolled in this cross-sectional study. Arterial stiffness was evaluated by pulse wave velocity (PWV). Neuromuscular symptoms were questioned. Participants wore a physical activity monitor (SenseWear((R)) Armband) for 4 consecutive days. Handgrip and quadriceps muscle strength were assessed by dynamometer. Functional exercise capacity was assessed by 6-minute walk test (6MWT).ResultsThere was no significant difference in sociodemographic variables between the groups. PWV was significantly higher in the SCH group (P=0.006). Physical activity duration and number of steps were significantly lower in the SCH group (P<0.05). There was significant difference in neuromuscular symptoms, handgrip and quadriceps muscle strength, and 6MWT distance between the groups (P<0.05).ConclusionsThis study demonstrates that women with SCH had lower PALs compared to healthy controls. Women with SCH should participate in exercise programs to increase physical activity and muscle strength to achieve adequate PALs.