Age-dependent and sex-dependent disparity in mortality in patients with adrenal incidentalomas and autonomous cortisol secretion: an international, retrospective, cohort study.

Deutschbein T., Reimondo G., Di Dalmazi G., Bancos I., Patrova J., Vassiliadi D. A., ...More

The lancet. Diabetes & endocrinology, vol.10, no.7, pp.499-508, 2022 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 10 Issue: 7
  • Publication Date: 2022
  • Doi Number: 10.1016/s2213-8587(22)00100-0
  • Journal Name: The lancet. Diabetes & endocrinology
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CAB Abstracts, EMBASE, Food Science & Technology Abstracts, MEDLINE, Veterinary Science Database
  • Page Numbers: pp.499-508
  • Dokuz Eylül University Affiliated: Yes

Abstract

Background The association between cortisol secretion and mortality in patients with adrenal incidentalomas is controversial. We aimed to assess all-cause mortality, prevalence of comorbidities, and occurrence of cardiovascular events in uniformly stratified patients with adrenal incidentalomas and cortisol autonomy (defined as non-suppressible serum cortisol on dexamethasone suppression testing).