Effects of high-dose intravenous methylprednisolone in children with acute rheumatic carditis


Akcoral A., Oran B., Tavli V., Unal N., Cevik N.

ACTA PAEDIATRICA JAPONICA, vol.38, no.1, pp.28-31, 1996 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 38 Issue: 1
  • Publication Date: 1996
  • Doi Number: 10.1111/j.1442-200x.1996.tb03430.x
  • Journal Name: ACTA PAEDIATRICA JAPONICA
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.28-31
  • Keywords: intravenous pulse therapy, methylprednisolone, rheumatic carditis, THERAPY, INHIBITION
  • Dokuz Eylül University Affiliated: No

Abstract

In order to measure the effects of high-dose intravenous methylprednisolone (HIVMP) and compare its efficiency with that of oral prednisolone (OP), 18 patients with active rheumatic carditis were studied. Ten patients received OF. while eight patients were treated with HIVMP. Clinical and laboratory responses to treatment were followed by sleeping pulse rate, systolic blood pressure, erythrocyte sedimentation rate (ESR), cardiothoracic ratio (CTR), PR interval on electrocardiogram. spectral and color flow imaging and Doppler echocardiographic findings: mitral and aortic regurgitant jet flow area, left atrial area, proximal width of mitral regurgitant jet area and regurgitation fractions.