Association between oxidative stress index and post-CPR early mortality in cardiac arrest patients: A prospective observational study

YÜCEL H., Turkdogan K. A., ZORLU A., AYDIN H., KURT R., YILMAZ M. B.

ANATOLIAN JOURNAL OF CARDIOLOGY, vol.15, no.9, pp.737-743, 2015 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 15 Issue: 9
  • Publication Date: 2015
  • Doi Number: 10.5152/akd.2014.5719
  • Journal Name: ANATOLIAN JOURNAL OF CARDIOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.737-743
  • Keywords: cardiopulmonary resuscitation, oxidative stress index, cardiac arrest, ISCHEMIA-MODIFIED ALBUMIN, NEURON-SPECIFIC ENOLASE, ELEVATION MYOCARDIAL-INFARCTION, CARDIOPULMONARY-RESUSCITATION, PREDICTOR, DISEASE, PROGNOSIS, DIAGNOSIS, RADICALS, SURVIVAL
  • Dokuz Eylül University Affiliated: No

Abstract

Objective: Cardiopulmonary resuscitation (CPR) is a series of lifesaving actions that improve the chance of survival following cardiac arrest (CA). Many clinical and laboratory parameters, such as the presence of asystole, out-of-hospital CPR, and duration of cardiac arrest, are associated with failed CPR in patients with CA. Asystole is a state of no cardiac electrical activity, along with the absence of contractions of the myocardium and absence of cardiac output. Oxidative stress index (OSI), which is the ratio of total oxidative status to total antioxidant status, increases by ischemia-reperfusion injury. We investigated whether OSI levels in patients with CA could predict early mortality after CPR.