Sugammadex use in liver transplantation: a case series and literature review

İYİLİKÇİ KARAOĞLAN L., ÖZBİLGİN Ş., Akan M., ÖZKARDEŞLER S., Duru L. S.

ANAESTHESIA PAIN & INTENSIVE CARE, vol.19, no.3, pp.376-379, 2015 (ESCI) identifier

  • Publication Type: Article / Article
  • Volume: 19 Issue: 3
  • Publication Date: 2015
  • Journal Name: ANAESTHESIA PAIN & INTENSIVE CARE
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus
  • Page Numbers: pp.376-379
  • Keywords: Liver transplantation, Sugammadex, Neuromuscular blockade, Endotracheal extubation, Rocuronium, Neuromuscular Nondepolarizing Agents
  • Dokuz Eylül University Affiliated: Yes

Abstract

Postoperative residual neuromuscular blockade is associated with significant morbidity in liver transplantation. We report postoperative outcomes of sugammadex in a case series of 6 adult patients underwent liver transplantation at our institution in 2013. Sugammadex administration did not lead to any differences in the patients' heart rates, mean arterial pressures and electrocardiograms. In this case series, we observed that administration of rocuronium and sugammadex was effective and safe in liver transplant recipients. Postoperative residual neuromuscular blockade reversal with sugammadex may reduce the risk of pulmonary complications in liver transplant recipients.