Antithrombin III pretreatment reduces neutrophil recruitment into the lung and skeletal muscle tissues in the rat model of bilateral lower limb ischemia and reperfusion: a pilot study.

Duru, S; Koca, U; Oztekin, S; Olguner, ÇİMEN; Kar, A; Coker, ŞADİYE; Ulukus, EMİNE; Tasci, C; Elar, Z

doi:10.1111/j.1399-6576.2005.00764.x

Antithrombin III pretreatment reduces neutrophil recruitment into the lung and skeletal muscle tissues in the rat model of bilateral lower limb ischemia and reperfusion: a pilot study.

Atıf İçin Kopyala

Duru S., Koca U., Oztekin S., Olguner Ç. G., Kar A., Coker C., ...Daha Fazla

Acta anaesthesiologica Scandinavica, cilt.49, sa.8, ss.1142-8, 2005 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 49 Sayı: 8
Basım Tarihi: 2005
Doi Numarası: 10.1111/j.1399-6576.2005.00764.x
Dergi Adı: Acta anaesthesiologica Scandinavica
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.1142-8
Anahtar Kelimeler: activated leukocytes, anti-inflammatory, antithrombin III, ischemia-reperfusion, myeloperoxidase, prostacyclin, TUMOR-NECROSIS-FACTOR, SYSTEMIC INFLAMMATORY RESPONSE, LOWER TORSO ISCHEMIA, FACTOR-ALPHA, INJURY, ENDOTOXIN, MYELOPEROXIDASE, INTERLEUKIN-1, SELECTIN, SHOCK
Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Background: Anti-inflammatory action of Antithrombin III (AT III) is still not well understood in ischemia/reperfusion (I/R) injury. In the present study, we aimed to investigate the anti-inflammatory action of AT III on remote lung and local skeletal muscle tissue injury in a rat model of bilateral lower limb I/R model.