A New Application Route of Nitrofurantoin: Preparation and Characterization of Novel Transdermal Formulations

ARICI M., KAVUKÇU S., TUNCAY TANRIVERDİ S., Arici A., Gidener S., GELAL A., ...Daha Fazla

CURRENT DRUG DELIVERY, cilt.14, sa.3, ss.394-405, 2017 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 14 Sayı: 3
  • Basım Tarihi: 2017
  • Doi Numarası: 10.2174/1567201813666160729095229
  • Dergi Adı: CURRENT DRUG DELIVERY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.394-405
  • Anahtar Kelimeler: Film formulations, gel formulations, microemulsions, nitrofurantoin, transdermal drug delivery, urinary tract infections, IN-VITRO RELEASE, SKIN PERMEATION, PHYSICOCHEMICAL CHARACTERISTICS, DICLOFENAC DIETHYLAMMONIUM, HAIRLESS MOUSE, OLEIC-ACID, DELIVERY, VIVO, PENETRATION, DRUGS
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Objectives: Nitrofurantoin is widely used in the prophylaxis of urinary-tract infections. The aim of this study was to develop and characterize innovative transdermal formulations of nitrofurantoin, to increase the patient compliance and decrease the adverse effects such as nausea and vomiting which limit the drug use in long-term.