A New Application Route of Nitrofurantoin: Preparation and Characterization of Novel Transdermal Formulations
CURRENT DRUG DELIVERY, vol.14, no.3, pp.394-405, 2017 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 14 Issue: 3
- Publication Date: 2017
- Doi Number: 10.2174/1567201813666160729095229
- Journal Name: CURRENT DRUG DELIVERY
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.394-405
- Keywords: Film formulations, gel formulations, microemulsions, nitrofurantoin, transdermal drug delivery, urinary tract infections
- Dokuz Eylül University Affiliated: Yes
Abstract
Objectives: Nitrofurantoin is widely used in the prophylaxis of urinary-tract infections. The aim of this study was to develop and characterize innovative transdermal formulations of nitrofurantoin, to increase the patient compliance and decrease the adverse effects such as nausea and vomiting which limit the drug use in long-term.