Evaluation of Systemic Levels of Neutrophilic Enzymes in Patients With Hypertension and Chronic Periodontitis

Turkoglu O., BARIŞ N., Tervahartiala T., Senarslan O., Sorsa T., ATİLLA F. G.

JOURNAL OF PERIODONTOLOGY, vol.85, no.7, pp.908-916, 2014 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 85 Issue: 7
  • Publication Date: 2014
  • Doi Number: 10.1902/jop.2013.130346
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.908-916
  • Keywords: Inflammation, hypertension, matrix metalloproteinases, neutrophils, periodontal diseases, tissue inhibitor of metalloproteinases, GINGIVAL CREVICULAR FLUID, ARGININE METHYL-ESTER, MATRIX METALLOPROTEINASE-8, TISSUE INHIBITOR, ENDOTHELIAL DYSFUNCTION, CARDIOVASCULAR RISK, LEARN DETERMINATION, SERUM-LEVELS, MMP-8, MARKERS
  • Dokuz Eylül University Affiliated: Yes


Background: Inflammation stimulates neutrophils to release their enzymes into the extracellular matrix. The aim of the present study is to investigate the serum levels of matrix metalloproteinase (MMP)-8, MMP-9, tissue inhibitor of MMP (TIMP)-1, myeloperoxidase (MPO), and neutrophil elastase (NE) in patients with hypertension and chronic periodontitis (CP).