Long-term treatment of persistent disseminated Nocardia cyriacigeorgica infection

Ozgenc O., Avci M., Ari A., Celebi I. Y., Coskuner S. A.

BRAZILIAN JOURNAL OF INFECTIOUS DISEASES, vol.18, no.5, pp.556-560, 2014 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 18 Issue: 5
  • Publication Date: 2014
  • Doi Number: 10.1016/j.bjid.2014.03.007
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.556-560
  • Keywords: Nocardia cyriacigeorgica, Chronic infection, Treatment, FARCINICA, THERAPY
  • Dokuz Eylül University Affiliated: Yes


In this paper a disseminated persistent Nocardia cyriacigeorgica infection in an immunocompetent patient is described. The patient's long-term treatment, as well as its implications for managing similar cases in the future, is emphasized. Presenting with high fever, multiple nodules, and ulcerative cutaneous lesions of body sites, the patient was treated with various antimicrobials. Under combined therapy, empyema and arthritis, leading to disseminated nocardiosis, were seen. The overall treatment course was 28 months. It can be concluded that the choice of the antibiotics and optimal duration of treatment are uncertain; therefore the treatment of nocardiosis requires expertise. (C) 2014 Elsevier Editora Ltda. All rights reserved.