Evaluation of metabolic syndrome and its components in patients with rosacea: a cross-sectional, case-control study

Ozbagcivan O., Ozturk T., Akarsu S., Ilknur T., Fetil E.

HONG KONG JOURNAL OF DERMATOLOGY & VENEREOLOGY, cilt.28, sa.2, ss.55-62, 2020 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 28 Sayı: 2
  • Basım Tarihi: 2020
  • Dergi Adı: HONG KONG JOURNAL OF DERMATOLOGY & VENEREOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE
  • Sayfa Sayıları: ss.55-62
  • Anahtar Kelimeler: Cardiovascular risk factors, metabolic syndrome, rosacea, ENDOPLASMIC-RETICULUM STRESS, OBESITY
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Introduction: Previous studies have suggested an association between cardiovascular disease and rosacea. However, there is still a paucity of data regarding its association with metabolic syndrome (MetS). Methods: The components of MetS were evaluated in 100 rosacea patients and 100 controls. Results: MetS was determined in 44% of the rosacea patients and 35% of the controls. Although the difference was not statistically significant (p=0.193), rosacea patients were more likely to have dyslipidaemia (p<0.001), insulin resistance (p=0.035), hypertension (p=0.009), higher atherogenic index (p<0.001) and a higher hypercoagulability (p=0.025) and inflammatory state (p=0.003) compared to controls. Conclusion: The results of this study support that rosacea patients should be screened routinely for the components of MetS such as dyslipidaemia, insulin resistance, hypertension and other cardiovascular risk factors.