A double-blind study of combination of clozapine with risperidone in patients with schizophrenia: Effects on cognition

Akdede, BERNA; ANIL YAĞCIOĞLU, AYŞE; ALPTEKİN, KÖKSAL; Turgut, Tolga; Tumuklu, Mevhibe; YAZICI, MÜMİN; Jayathilake, Karu; Tunca, Zeliha; Gogus, Ahmet; Meltzer, Herbert

doi:10.4088/jcp.v67n1211

A double-blind study of combination of clozapine with risperidone in patients with schizophrenia: Effects on cognition

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Akdede B. B., ANIL YAĞCIOĞLU A. E., ALPTEKİN K., Turgut T. I., Tumuklu M., YAZICI M. K., ...More

JOURNAL OF CLINICAL PSYCHIATRY, vol.67, no.12, pp.1912-1919, 2006 (SCI-Expanded)

Publication Type: Article / Article
Volume: 67 Issue: 12
Publication Date: 2006
Doi Number: 10.4088/jcp.v67n1211
Journal Name: JOURNAL OF CLINICAL PSYCHIATRY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Social Sciences Citation Index (SSCI), Scopus
Page Numbers: pp.1912-1919
Dokuz Eylül University Affiliated: Yes

Abstract

Background: Atypical antipsychotic drugs produce improvement in some domains of cognition as well as psychopathology in patients with schizophrenia. However, the effect of combinations of atypical antipsychotic drugs on cognitive function is unknown. The aim of this study was to compare the effect of risperidone or placebo on cognitive function in patients with schizophrenia who were previously treated with clozapine monotherapy.