Role of apoptosis, bcl-2 and bax protein expression in premature rupture of fetal membranes

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Sagol S., Sagol Ö., Ozkal S., Asena U.

JOURNAL OF REPRODUCTIVE MEDICINE, vol.47, no.10, pp.809-815, 2002 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 47 Issue: 10
• Publication Date: 2002
• Journal Name: JOURNAL OF REPRODUCTIVE MEDICINE
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.809-815
• Keywords: fetal membranes, premature rupture, apoptosis, bcl-2 genes, bax, CELL-DEATH, PLACENTAL APOPTOSIS, DEGRADATION, ACTIVATION, PREGNANCY, LABOR
• Dokuz Eylül University Affiliated: Yes

Abstract

OBJECTIVE: To examine the degree of apoptosis in human fetal membranes associated with premature rupture Of membranes (PROM) as compared with normal pregnancies and to evaluate the expression of proapoptotic bax and antiapoptotic bcl-2 gene products.