Nano/Microcellulose-Doped Textile-Based Carboxymethyl Chitosan-Polyethylene Glycol Hydrogels For Surgical Dressings

TÜRKOĞLU G. C., ZİYLAN A., KARAVANA S. Y., AYDIN KÖSE F., ÖNDER T., ERDOĞAN Ü. H., ...Daha Fazla

XVth International Izmir Textile and Apparel Symposium - IITAS 2021, İzmir, Türkiye, 26 - 28 Ekim 2021, ss.397-403, (Tam Metin Bildiri)

  • Yayın Türü: Bildiri / Tam Metin Bildiri
  • Basıldığı Şehir: İzmir
  • Basıldığı Ülke: Türkiye
  • Sayfa Sayıları: ss.397-403
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

In this study, soft hydrogel layers reinforced with cotton nonwoven were produced to use as a surgical dressing. Solution consisting of two polymers (O-carboxymethyl chitosan and polyethylene glycol) were chemically cross-linked using polyethylene glycol diglycidyl ether. Optimum hydrogel formulation was determined considering mechanical parameters. After casting of the selected formulation onto nonwovens, samples were freeze-dried. To increase the swelling capacity of the hydrogels, nano/micro-sized cellulose was added. Physical features, dynamic fluid handling capacity, water vapor permeability, morphology (SEM), and chemical structure (FT-IR) were examined. Antibacterial and in vitro cytotoxicity assays were applied to the formulation showing the best characteristics.