The effects of intravenous iron treatment on oxidant stress and erythrocyte deformability in hemodialysis patients

Cavdar C., Temiz A., Yenicerioglu Y., Caliskan S., Celik A., Sifil A., ...More

SCANDINAVIAN JOURNAL OF UROLOGY AND NEPHROLOGY, vol.37, no.1, pp.77-82, 2003 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 37 Issue: 1
  • Publication Date: 2003
  • Doi Number: 10.1080/00365590310008758
  • Journal Name: SCANDINAVIAN JOURNAL OF UROLOGY AND NEPHROLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.77-82
  • Keywords: hemodialysis, iron, oxidant stress, erythrocyte deformability, CHRONIC-RENAL-FAILURE, LIPID-PEROXIDATION, SPLENIC HEMOLYSIS, OXIDATIVE STRESS, CELL RIGIDITY, ERYTHROPOIETIN, MEMBRANE, ABNORMALITIES, ANEMIA, INJURY
  • Dokuz Eylül University Affiliated: Yes

Abstract

Background: It is well known that free iron causes oxidant stress to increase. However data concerning whether intravenously (IN) administered iron in maintenance doses (10-20 mg) gives rise to increased oxidant stress and disturbed erythrocyte deformability (EDEF) in hemodialysis (HD) patients is lacking. In the present study, we aimed to evaluate and compare the effects of IN iron on oxidant stress and EDEF.