Antibiotic-impregnated xenografts in the treatment of chronic osteomyelitic cavities. Seven cases followed for 3 to 5 years

Creative Commons License

Seber S., Günal I., Göktürk E.

International Orthopaedics, vol.22, no.3, pp.197-199, 1998 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 22 Issue: 3
  • Publication Date: 1998
  • Doi Number: 10.1007/s002640050241
  • Journal Name: International Orthopaedics
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.197-199
  • Dokuz Eylül University Affiliated: Yes


We describe seven patients with chronic osteomyelitis which developed in 3 following operation and in 4 after trauma. The treatment consisted of removal of dead tissue and filling the resulting cavities with gentamicin-impregnated xenografts. No antibiotics were used postoperatively. Urine gentamicin levels were above 0.5 μg/ml for 8 days. The patients were followed up for at least 3.5 years and neither clinical nor laboratory signs of infection were detected. These results lead us the conclusion that gentamicin-impregnated xenografts may have a place in the treatment of chronic osteomyelitis.