Erectile function and late-onset hypogonadism symptoms related to lower urinary tract symptom severity in elderly men


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BOZKURT O., Bolat D., Demir O., ÜÇER O., Sahin A., Ozcift B., ...More

ASIAN JOURNAL OF ANDROLOGY, vol.15, no.6, pp.785-789, 2013 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 15 Issue: 6
  • Publication Date: 2013
  • Doi Number: 10.1038/aja.2013.44
  • Journal Name: ASIAN JOURNAL OF ANDROLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.785-789
  • Keywords: ageing male, erectile dysfunction, lower urinary tract symptoms, symptomatic late-onset hypogonadism, symptom scores, testosterone, MALE SEXUAL DYSFUNCTION, REPLACEMENT THERAPY, TESTOSTERONE THERAPY, INTERNATIONAL INDEX, ANDROGEN DEFICIENCY, JAPANESE PATIENTS, AGING MALE, HORMONES, EPIDEMIOLOGY, ASSOCIATION
  • Dokuz Eylül University Affiliated: Yes

Abstract

The aim of this study was to evaluate the relationship between lower urinary tract symptoms (LUTSs), erectile dysfunction (ED) and symptomatic late-onset hypogonadism (SLOH) in ageing men in the Aegean region of Turkey. Five hundred consecutive patients >40 years old who had been in a steady sexual relationship for the past 6 months and were admitted to one of six urology clinics were included in the study. Serum prostate-specific antigen and testosterone levels and urinary flow rates were measured. All patients filled out the International Prostate Symptom Score and Quality of Life (IPSS-QoL), International Index of Erectile Function (IIEF) and Aging Males' Symptoms (AMS) scale forms. Of the patients, 23.9% had mild LUTSs, 53.3% had moderate LUTSs and 22.8% had severe LUTSs. The total testosterone level did not differ between groups. Additionally, 69.6% had ED. The presence of impotence increased with increasing LUTS severity. Symptomatic late-onset hypogonadism (AMS>27) was observed in 71.2% of the patients. The prevalence of severe hypogonadism symptoms increased with the IPSS scores. A correlation analysis revealed that all three questionnaire scores were significantly correlated. In conclusion, LUTS severity is an age-independent risk factor for ED and SLOH. LUTS severity and SLOH symptoms appear to have a strong link that requires etiological and biological clarification in future studies.