Prevention of heterotopic ossification after total hip replacement - A prospective comparison of indomethacin and salmon calcitonin in 60 patients

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Gunal I., Hazer B., Seber S., Gokturk E., Turgut A., KÖSE N.

ACTA ORTHOPAEDICA SCANDINAVICA, vol.72, no.5, pp.467-469, 2001 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 72 Issue: 5
  • Publication Date: 2001
  • Doi Number: 10.1080/000164701753532781
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.467-469
  • Dokuz Eylül University Affiliated: No


We did a prospective consecutive study of prophylaxis for heterotopic ossification (HO) comparing indomethacin (100 mg/day) and salmon calcitonin (3 MRC-U/kg/day) for 14 days. Each group consisted of 30 patients. 19 patients in the indomethacin group and 2 in the calcitonin group developed HO. We conclude that use of calcitonin in the prophylaxis of HO after total hip replacement is more effective than indomethacin.