Long-term monitoring of Graves' disease in children and adolescents: a single-center experience


Tunc S., Koprulu O., Ortac H., Nalbantoglu O., Dizdarer C., DEMİR K., ...More

TURKISH JOURNAL OF MEDICAL SCIENCES, vol.49, no.2, pp.464-471, 2019 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 49 Issue: 2
  • Publication Date: 2019
  • Doi Number: 10.3906/sag-1804-177
  • Journal Name: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.464-471
  • Keywords: Graves' disease, hyperthyroidism, antithyroid drugs, ANTITHYROID DRUG-TREATMENT, PUBERTAL CHANGES, HYPERTHYROIDISM, THERAPY, REMISSION, METHIMAZOLE, MANAGEMENT, PATTERN, PROPYLTHIOURACIL, HEPATOTOXICITY
  • Dokuz Eylül University Affiliated: Yes

Abstract

Background/aim: Graves' disease (GD) is more severe, requires a more complex treatment, and has a lower probability of achieving remission in children than in adults. 'there is no consensus on the appropriate duration of antithyroid drug (ATD) treatment. Surgical or radioactive iodine (RAI) treatments are not definitive and generally result in permanent hypothyroidism. This study's goal was examining the effectiveness of ATD treatment in children and adolescents with GD and determining the risk factors of remission and relapse.