Long-term monitoring of Graves' disease in children and adolescents: a single-center experience

Tunc S., Koprulu O., Ortac H., Nalbantoglu O., Dizdarer C., DEMİR K., ...Daha Fazla

TURKISH JOURNAL OF MEDICAL SCIENCES, cilt.49, sa.2, ss.464-471, 2019 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 49 Sayı: 2
  • Basım Tarihi: 2019
  • Doi Numarası: 10.3906/sag-1804-177
  • Dergi Adı: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.464-471
  • Anahtar Kelimeler: Graves' disease, hyperthyroidism, antithyroid drugs, ANTITHYROID DRUG-TREATMENT, PUBERTAL CHANGES, HYPERTHYROIDISM, THERAPY, REMISSION, METHIMAZOLE, MANAGEMENT, PATTERN, PROPYLTHIOURACIL, HEPATOTOXICITY
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Background/aim: Graves' disease (GD) is more severe, requires a more complex treatment, and has a lower probability of achieving remission in children than in adults. 'there is no consensus on the appropriate duration of antithyroid drug (ATD) treatment. Surgical or radioactive iodine (RAI) treatments are not definitive and generally result in permanent hypothyroidism. This study's goal was examining the effectiveness of ATD treatment in children and adolescents with GD and determining the risk factors of remission and relapse.