Neuroprotective effect of boron-containing compounds on Alzheimer's and Parkinson’s diseases Alzheimer ve Parkinson hastalıklarında bor içeren bileşiklerin nörokoruyucu etkisi

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Bitmez B., Balbal B.

Journal of Boron, vol.9, no.1, pp.42-51, 2024 (Scopus, TRDizin) identifier identifier

  • Publication Type: Article / Review
  • Volume: 9 Issue: 1
  • Publication Date: 2024
  • Doi Number: 10.30728/boron.1408368
  • Journal Name: Journal of Boron
  • Journal Indexes: Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.42-51
  • Keywords: Alzheimer disease, Boron, Neurodegeneration, Neuroinflammation, Parkinson disease
  • Open Archive Collection: AVESIS Open Access Collection
  • Dokuz Eylül University Affiliated: Yes

Abstract

This review describes the effects of boron-containing compounds on the neurodegeneration process. Boron-containing compounds show various protective effects on neurons. Recent studies have shown that boron supplementation leads to increased antioxidant defense mechanisms in neurons, suppressing inflammation and exhibiting the potential to protect against oxidative damage. In this review article, studies investigating the neuroprotective effects of boron-containing compounds were examined and it was determined that further studies were needed on the application of boron-containing compounds as drugs to specific targets in the treatment of neurodegenerative diseases.