Significance of P-glycoprotein, p53, and survivin expression in renal cell carcinoma.

Baytekin F., Tuna B., Mungan U., ASLAN G., YÖRÜKOĞLU K.

Urologic oncology, vol.29, no.5, pp.502-7, 2011 (SCI-Expanded, Scopus) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 29 Issue: 5
  • Publication Date: 2011
  • Doi Number: 10.1016/j.urolonc.2009.09.001
  • Journal Name: Urologic oncology
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.502-7
  • Keywords: P-glycoprotein, p53, Survivin, Renal cell carcinoma, Immunohistochemistry
  • Dokuz Eylül University Affiliated: Yes

Abstract

Objectives: This study addresses the relationship between cell cycle control protein p53, apoptosis inhibitor gene survivin, and chemotherapy resistance protein P-glycoprotein (P-gp) expression, and their prognostic impact in renal cell carcinoma (RCC).