Wiener Tierarztliche Monatsschrift, cilt.95, sa.11, ss.263-268, 2008 (SCI-Expanded)
The aim of this study was to investigate the effectiveness of Thuja occidentalis and Urtica urens in pseudopregnant bitches. Clinically pseudopregnant bitches (n=38)
were assigned per random to groups as follows: Group I:
Thuja occidentalis D30 (8 globules, 3 times a day, per os,
n=15); Group II: Urtica urens D6 (8 globules, 3 times a day,
per os, n=15); Group III: naloxone (control group, 0.01
mg/kg, twice daily, s.c., n=8). Treatments were continued
until clinical signs resolved. Animals were classified as no,
mild, moderate, and severe (score –, +, ++, and +++)
according to the clinical signs of mammary glands and
behavioural signs during the study. Bitches were examined
at 3-5 days intervals by means of adspection and palpation
until clinical signs resolved.
Successful recovery rates (100 %) were found in Group
I and II. Application of naloxone was found to be successful in only 3 of 8 bitches (37.5 %). Mean duration of treatments in Group I, II and III was 11.6±4.6 (min-max: 3-18)
days, 13.5±3.7 (min-max: 6-19) days and 14.3±5.9 (minmax: 10-21) days, respectively. During treatment with Thuja occidentalis D30 and Urtica urens D6, the percentages
of bitches with behavioural problems significantly
decreased within 3-5 days from 33.3 % to 6.7 % (p=0.033)
and from 66.7 % to 33.3 % (p=0.050), respectively. All
bitches treated with Thuja occidentalis D30 or Urtica urens
D6 showed normal behaviour within 10 days after onset of
treatments but 2 bitches in the naloxone group kept showing behavioural signs until Days 15-20 of treatment. Concerning mammary gland scores, treatments yielded significantly higher success rates in Group I and Group II (100 %
in both groups) compared to the success rate observed in
Group III (37.5 %; p=0.012). No side effects were observed
during the study. In conclusion, the homeopathic agents
Thuja occidentalis D30 and Urtica urens D6 proved to be
effective and safe in pseudopregnant bitches.