Major psychoses with mixed psychotic and mood symptoms: are mixed psychoses associated with different neurobiological markers?


BORA İ. E., Yucel M., Fornito A., Berk M., Pantelis C.

ACTA PSYCHIATRICA SCANDINAVICA, vol.118, no.3, pp.172-187, 2008 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Review
  • Volume: 118 Issue: 3
  • Publication Date: 2008
  • Doi Number: 10.1111/j.1600-0447.2008.01230.x
  • Journal Name: ACTA PSYCHIATRICA SCANDINAVICA
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Social Sciences Citation Index (SSCI), Scopus
  • Page Numbers: pp.172-187
  • Keywords: neuropsychology, brain imaging, electrophysiology, bipolar disorder, schizophrenia, schizoaffective disorder, GRAY-MATTER VOLUME, 1ST-EPISODE AFFECTIVE PSYCHOSIS, SENSORIMOTOR GATING DEFICITS, BIPOLAR DISORDER PATIENTS, SCHIZOAFFECTIVE DISORDER, SCHIZOPHRENIC-PATIENTS, PREPULSE INHIBITION, CYCLOID PSYCHOSES, EUTHYMIC PATIENTS, WORKING-MEMORY
  • Dokuz Eylül University Affiliated: Yes

Abstract

Objective: Evidence related to overlapping clinical and genetic risk factors in schizophrenia and bipolar disorder (BD) have raised concerns about the validity of 'Kraepelinian dichotomy'. As controversies mainly arise in mixed psychoses that occupy the intermediate zone between schizophrenia and BD, investigating neurobiological markers of mixed psychoses may be relevant to understanding the nature of psychotic disorders.