Galectin-3 levels in patients with hypertrophic cardiomyopathy and its relationship with left ventricular mass index and function.

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Tuluce S. Y., Tuluce K., Cil Z., EMREN S. V., Akyildiz Z. I., Ergene O.

Anatolian journal of cardiology, vol.16, no.5, pp.344-8, 2016 (SCI-Expanded, Scopus, TRDizin) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 16 Issue: 5
  • Publication Date: 2016
  • Doi Number: 10.5152/anatoljcardiol.2015.6191
  • Journal Name: Anatolian journal of cardiology
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.344-8
  • Keywords: Galectin-3, hypertrophic cardiomyopathy, left ventricular mass index, strain imaging
  • Open Archive Collection: AVESIS Open Access Collection
  • Dokuz Eylül University Affiliated: Yes

Abstract

Objective: Cardiac fibrosis is an important contributor to adverse left ventricular (LV) remodeling and arrhythmias in patients with hypertrophic cardiomyopathy (HCM). Galectin-3 (Gal-3) is a novel marker of cardiac fibrosis and inflammation. In this study, we investigated Gal-3 levels in patients with HCM and controls and assessed the relationship between Gal-3 level and echocardiographic indices using strain echocardiography in patients with HCM.