An overview of biomolecules, immobilization methods and support materials of biosensors
SENSOR REVIEW, vol.39, no.3, pp.377-386, 2019 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 39 Issue: 3
- Publication Date: 2019
- Doi Number: 10.1108/sr-04-2018-0084
- Journal Name: SENSOR REVIEW
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.377-386
- Keywords: Biomolecule, Biosensors, Biosensor characteristics, Immobilization, Support materials
- Dokuz Eylül University Affiliated: Yes
Abstract
Purpose Traditional analytical methods are often time-consuming and require bulky instruments, making their widespread implementation challenging. This paper aims to represent the principal concepts of biosensors as an introduction of this technology to readers and offers a comprehensive understanding of its functions. Design/methodology/approach The authors provide descriptions of the components, characteristics and advantages of biosensors along with the immobilization methods, followed by a brief discussion. Findings A biosensor is an analytical device comprising a specific biomolecule and a transducer in conjunction with an output system. The biomolecule recognizes a specific target which leads to a change in physicochemical properties of a system. This biorecognition phenomenon is later converted into a detectable signal by the transducer. Biosensors can essentially serve as rapid and cost-effective devices with excellent sensitivity and specificity for critical purposes in innumerable fields, ranging from scientific research to day-to-day applications. Originality/value Here, the authors explain and discuss the approaches and challenges with the aim of leading to an interest in biosensor development and improving their applications.