Akademik Veri Yönetim Sistemi
ESUR 2025 Annual Meeting Stockholm, Stockholm, İsveç, 25 - 28 Eylül 2025, ss.1-5, (Tam Metin Bildiri)
Title: Diagnostic Value of NODE-RADS in Bladder Cancer: Association with
Histopathology and Imaging Characteristics
Objectives
To assess the ability of the NODE-RADS scoring system to predict lymph node
metastasis in bladder cancer and to explore its relationship with histopathological
results and radiologic features.
Materials and Methods
This retrospective study included 48 patients with bladder cancer who underwent
cross-sectional imaging before surgery. Lymph nodes were scored according to
NODE-RADS, and histopathological results were reviewed. Associations were
analyzed between NODE-RADS scores and lymph node status, tumor grade,
vascular invasion, nodal size (short and long axes), and morphologic imaging
findings. Chi-square and ANOVA tests were used for statistical analysis.
Results
Among 48 patients, 11 (22.9%) had histopathologically proven nodal metastases.
None of the patients with NODE-RADS scores of 1 (n=13) or 2 (n=12) had
metastases. One patient with a score of 3 (n=12) had a positive node. All patients
with scores of 4 (n=6) and 5 (n=5) had metastatic involvement.
Using a threshold of ≥3, NODE-RADS achieved a sensitivity of 100% and a
specificity of 88.9%. Higher scores were significantly linked with increased nodal
dimensions (p < 0.001), irregular contours, necrosis, and spherical shape (p < 0.05).
No significant correlation was found with tumor grade, vascular invasion, or sex.
Conclusions
NODE-RADS is a reliable and practical tool for predicting nodal metastasis in bladder
cancer. It may enhance radiological staging and support treatment decisions when
used routinely in preoperative evaluation.