Quantitative phytochemical analysis of Inula viscosa extracts from Izmir, Türkiye


Erol A., Gökbayrak Ö., Aktaş S.

5th international eurasian conference on biological and chemical sciences, Ankara, Türkiye, 23 - 25 Kasım 2022, ss.1238

  • Yayın Türü: Bildiri / Tam Metin Bildiri
  • Basıldığı Şehir: Ankara
  • Basıldığı Ülke: Türkiye
  • Sayfa Sayıları: ss.1238
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Inula viscosa (L.) is one of the most used medicinal plants in countries of the Mediterranean region. I.viscosa has been used for many years in folk medicine for its anti-inflammatory, antipyretic, antiseptic, and antiphlogistic activities, and for different diseases. This study aimed to assay phytochemical analysis and antioxidant activity from different parts and different methods of Inula viscosa extract. After 300 kg of plants collected in September 2020 were separated as leaves, flowers, stems, and aerial parts. These different parts were extracted by maceration method, using different solvents (50% ethanol, 70% ethanol, methanol, water) and their % yield was calculated. Thus, it was decided to use the aerial parts of extract obtained by maceration with 70% ethanol solvent for this study. After that, total phenolic compound, total flavonoid compound ratios, and antioxidant activity were evaluated. Inula viscosa extract showed antioxidant activity and had a strong correlation with total flavonoid content. Our future goals are to conduct in vitro, in-vivo, and ex-vivo experiments of Inula viscosa, to elucidate its molecular mechanisms of action and to investigate its effects on different diseases. Thanks to the increase in studies to be carried out on such medicinal plants, which are frequently used among the public, it is thought that the side effects encountered because of misuse can be minimized by preparing reliable, dose-specific, modern phytotherapeutic preparations. This project has the code 2020.KB.MLT.005 and was supported by the Dokuz Eylül University,Department of  Scientific Research Project.

Keywords: Inula viscosa, Extraction, Antioxidant, Phenolic Compound, Flavonoid Content, Medicinal plants