Akademik Veri Yönetim Sistemi
29th Wonca Europe Conference, Dublin, İrlanda, 25 - 28 Eylül 2024, ss.1015, (Özet Bildiri)
Introduction
Hereditary blood disorders, especially thalassemia and sickle cell anemia, represent a significant public health issue both in Turkey and globally. This study aims to assess the rates and outcomes of hemoglobinopathy screening among couples seeking premarital counseling at the Training Family Health Center of Dokuz Eylul Universşity , within the National Screening Program from 2018 to 2024, using health record system data.
Method
This descriptive retrospective investigation analyzed data from the health record system for individuals screened for hemoglobinopathies at Dokuz Eylül University's Training Family Health Center from 2018 to 2024. A total of 1006 patients underwent premarital screening during this period. The study included all patients without sampling. Electrophoresis results obtained by the HPLC method were retrospectively analyzed for patients recorded in the health record system.
Results
Out of 1006 applicants, 509 (50.5%) were male, and 497 (49.5%) were female. The hemoglobinopathy prevalence was 1.8%. Among male patients, 14 (2.7%) were carriers, and among female patients, 5 (1%) were carriers. Carrier distribution showed that 11 individuals had MCV<79 fl and HbA2 >3.5, 3 had HbA2>3.5 and HbF>2, 4 had HbS, and 1 had HbD+.
Conclusion
Premarital screening for hemoglobinopathies is crucial in identifying carriers and preventing the transmission of these genetic disorders. The relatively low incidence of hemoglobinopathy among the screened population highlights the screening program's effectiveness in detecting at-risk individuals. Efforts to expand the reach and impact of such screening programs are necessary to ensure early detection and management of hereditary blood disorders, as demonstrated by the health record system data.