Akademik Veri Yönetim Sistemi
Turk Anesteziyoloji ve Reanimasyon, cilt.25, sa.10, ss.438-446, 1997 (Scopus)
In this study we examined the effectiveness midazolam-ketamin combination, midazolam and diazepam in premedication of children and evaluated the effects on hemodynamic and respiratory parameters. 60 children, aged 1-10 yr, undergoing elective surgery were divided into three groups. All cases were premedicated 30 minutes before operation with diazepam 0.2 mg/kg and atropin 0.02 mg/kg or midazolam 0.5 mg/kg and atropin 0.02 mg/kg or midazolam 0.3 mg/kg and ketamine 5 mg/kg and atropin 0.02 mg/kg in a maximal volume of 0.4 mL/kg cherry drink. Heart rate, arterial blood pressure, peripheric oxygen saturation, respiratory rate, sedation and anxiolizis scores were recorded before premedication, every fifteen minutes and induction of anaesthesia and recovery. Results were evaluated statistically. Sedation scores were significantly higher in group III for 15 min, 30 min and induction period evaluations. Face mask tolerance and separation from the parents were better in groups II and III. We concluded that oral midazolam- ketamine combination can be administered easily and safely to provide sufficient sedation, comfortable anesthesia induction and postoperative recovery for pediatric premedication.