Akademik Veri Yönetim Sistemi
SENDROM, cilt.21, sa.3, ss.30-37, 2009 (Scopus)
Viral hepatitis remains a major health problem. Hepatitis G Virus (HGV) is a RNA virus belonging to the Flaviviridae family. It shows a partial homology with Hepatitis C Virus (HCV). HGV has been identified in healthy blood donors, injecting drug users, people undergoing haemodialysis, blood or blood products recipients, people affected by other liver diseases (including viral hepatitis) and people without any known risk factor. HGV replicates within cells of the haemopoietic lineage, in particular lymphocytes. No disease has been associated with HGV infection. It is usually transmitted parenterally human immunodeficiency virus (HIV) infected persons. Co-infection with HGV and HIV leads to improved morbidity and mortality for the HIV infected individual and slows progression to acquired immunodeficiency syndrome. In this artical presents the history of the discovery of HGV, its molecular biology and some methods of detection; clinic sings of HGV infection, coinfections of HGV and HIV also are discussed.