Predictors of Paroxysmal Atrial Fibrillation in Patients With Chronic Obstructive Pulmonary Disease

Yurdam F. S., Şentürk B., Kış M.

12th International Hippocrates Congress on Medical and Health Sciences, Ankara, Türkiye, 1 - 02 Eylül 2023, ss.220-221

  • Yayın Türü: Bildiri / Özet Bildiri
  • Basıldığı Şehir: Ankara
  • Basıldığı Ülke: Türkiye
  • Sayfa Sayıları: ss.220-221
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Objective: AF is the most common chronic arrhythmia in adults.Risk factors for AF are advanced age, male gender, hypertension, diabetes mellitus, coronary artery disease, heart valve disease, heart failure, chronic kidney failure, hyperthyroidism, and smoking.COPD is one of the most common diseases characterized by progressive airflow limitation and is a predisposing factor for AF.Determining the predictive factors for paroxysmal atrial fibrillation (PAF) in COPD may be useful for identifying risky groups, early detection of patients at risk of AF, and the opportunity for early treatment.Methods: A total of 109 consecutive patients with a diagnosis of COPD who underwent 24-hour Holter ECG were included in the study. They were divided into two groups as those who did not have PAF on Holter ECG (Group 1) and those who were found (Group 2).Regression analysis was performed for significant parameters associated with paroxysmal AF.Results:109 patients included in the study were divided into two groups according to Holter ECG results: group 1(83 patients) (sinus rhythm), group 2(26 patients) (PAF). The median age of the patients was 66 (58-76) years and 75 (60-84) years in group 2, which was 64 (53-72) years statistically significantly higher than group 1 (p=0.001). LVEF value was 44% (39-48) lower in group 2 and 55% (48-60) lower than group 1 (p<0.001). In multivariate regression analysis, In patients with COPD, age (OR:1.053,95%CI:1.004-1.104,p=0.032), ejection fraction (OR:0.892,95%CI:0.807-0.987,p=0.028), moderate-severe mitral stenosis (OR:0.076,95%CI:0.008- 0.76,p=0.028) and SII (OR:1.003,95%CI:1.001-1.005,p=0.012) were independent predictors of paroxysmal AF in Holter ECG.Conclusion:PAF can be detected in Holter ECG even if the electrocardiography is normal in patients with COPD.This may be beneficial in terms of early detection and initiation of treatment in patients with COPD who are at risk of AF and to prevent AF complications. Advanced age, low LVEF and high SII are predictive parameters of paroxysmal AF in patients with COPD.