The effect of strict rate control on B-type natriuretic peptide values and echocardiographic parameters in chronic atrial fibrillation


Ozkurt Y., ÖZPELİT E., Aslan O., GÖLDELİ Ö.

KARDIOLOGIA POLSKA, vol.72, no.10, pp.934-940, 2014 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 72 Issue: 10
  • Publication Date: 2014
  • Doi Number: 10.5603/kp.a2014.0092
  • Journal Name: KARDIOLOGIA POLSKA
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.934-940
  • Keywords: atrial fibrillation, heart rate, B-type natriuretic peptide, cardiac remodelling, VENTRICULAR DIASTOLIC DYSFUNCTION, HEART-RATE, RISK-FACTOR, MANAGEMENT, LENIENT, DISEASE
  • Dokuz Eylül University Affiliated: Yes

Abstract

Background: There have been conflicting results about the role of strict rate control on cardiovascular outcomes in patients with chronic atrial fibrillation (AF). To date, large clinical studies have not shown a net clinical benefit derived from the current trend to specify the target ventricular rate according to the patient's own clinical and laboratory characteristics. Although the existing literature shows no superiority of strict rate control in clinical end points, it is difficult to assess the pure rate effect without commonly coexisting medication side effects which can also influence clinical end points.