Evaluation of Neoadjuvant Chemotherapy Response with Dynamic Contrast Enhanced Breast Magnetic Resonance Imaging in Locally Advanced Invasive Breast Cancer

Gezer N. S., Orbay Ö., Balcı P., Güray Durak M., Demirkan H. M. B., Saydam S.

Meme Sağlığı Dergisi, vol.10, no.2, pp.111-118, 2014 (Peer-Reviewed Journal) identifier identifier

  • Publication Type: Article / Article
  • Volume: 10 Issue: 2
  • Publication Date: 2014
  • Doi Number: 10.5152/tjbh.2014.2035
  • Journal Name: Meme Sağlığı Dergisi
  • Journal Indexes: TR DİZİN (ULAKBİM)
  • Page Numbers: pp.111-118
  • Keywords: Cancer, chemotherapy, breast, MRI, neoadjuvant, response
  • Dokuz Eylül University Affiliated: Yes


Objective: The reliability of traditional methods such as physical examination, ultrasonography (US) and mammography is limited in determining the type of treatment response in patients with neoadjuvant chemotherapy (NAC) application for locally advanced breast cancer (LABC). Dynamic contrast-enhanced magnetic resonance imaging (MRI) is gaining popularity in the evaluation of NAC response. This study aimed to compare NAC response as determined by dynamic contrast-enhanced breast MRI in patients with LABC to histopathology that is the gold standard; and evaluate the compatibility of MRI, mammography and US with response types.