Relationship between Serum Adipocyte Fatty Acid-Binding Protein Levels and Systemic Inflammation in Hemodialysis Patients

Korucu B., Derici M. K., Deger S. M., Cokay A., HELVACI Ö., Elbeg S., ...Daha Fazla

TURKISH JOURNAL OF NEPHROLOGY, cilt.29, sa.2, ss.115-121, 2020 (ESCI) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 29 Sayı: 2
  • Basım Tarihi: 2020
  • Doi Numarası: 10.5152/turkjnephrol.2020.3686
  • Dergi Adı: TURKISH JOURNAL OF NEPHROLOGY
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.115-121
  • Anahtar Kelimeler: Adipocyte fatty acid-binding protein, cardiovascular diseases, hemodialysis, systemic inflammation, EPICARDIAL ADIPOSE-TISSUE, LIPID-METABOLISM, APOLIPOPROTEIN-E, OBESITY, BIOMARKER, AP2, EXPRESSION, DEFICIENT, DISEASE, PREDICT
  • Dokuz Eylül Üniversitesi Adresli: Hayır

Özet

Objective: Adipocyte fatty acid-binding protein (A-FABP) is expressed in adipose tissue and macrophages. It regulates cholesterol trafficking and is involved in atherosclerosis formation. A-FABP levels are associated with cardiovascular diseases (CVDs) in patients with or without chronic kidney disease. In this study, we evaluated A-FABP levels in healthy controls and hemodialysis (HD) patients and compared the results with C-reactive protein (CRP) and interleukin-6 (IL-6) levels to determine their relationship with systemic inflammation.