What is the meaning of standard venous admixture formula results in septic patients?

Koca U.

PHYSIOLOGICAL MEASUREMENT, vol.27, no.1, 2006 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 27 Issue: 1
  • Publication Date: 2006
  • Doi Number: 10.1088/0967-3334/27/1/n01
  • Journal Name: PHYSIOLOGICAL MEASUREMENT
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Keywords: intrapulmonary shunt, oxygen consumption, oxygen delivery, oxygen content, oxygen extraction ratio, venous admixture, CRITICALLY-ILL PATIENTS, OXYGEN-CONSUMPTION, NONINVASIVE MEASUREMENT, INDIRECT CALORIMETRY, CARDIAC-OUTPUT
  • Dokuz Eylül University Affiliated: No

Abstract

The standard venous admixture formula is widely used in the bedside assessment of intrapulmonary shunt in intensive care units. The intrapulmonary shunt fraction calculated by the standard venous admixture formula is affected by the systemic oxygen extraction ratio and thus reflects both systemic and intrapulmonary shunts, especially in septic patients with decreased oxygen extraction ratios. The standard venous admixture formula may cause misestimation of the intrapulmonary shunt fraction, especially in septic patients. Inert gas rebreathing techniques and simultaneous measurement of cardiac output by thermodilution and oxygen consumption by indirect calorimetry may be useful in septic patients.