Role of lipooligosaccharide in the attachment of <i>Moraxella catarrhalis</i> to human pharyngeal epithelial cells

Akgul, GÜLCAN; Erturk, A; Turkoz, M; Turan, T; Ichinose, A; Nagatake, T; Ahmed, K

doi:10.1111/j.1348-0421.2005.tb03685.x

Role of lipooligosaccharide in the attachment of <i>Moraxella catarrhalis</i> to human pharyngeal epithelial cells

Akgul G., Erturk A., Turkoz M., Turan T., Ichinose A., Nagatake T., ...Daha Fazla

MICROBIOLOGY AND IMMUNOLOGY, cilt.49, sa.10, ss.931-935, 2005 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 49 Sayı: 10
Basım Tarihi: 2005
Doi Numarası: 10.1111/j.1348-0421.2005.tb03685.x
Dergi Adı: MICROBIOLOGY AND IMMUNOLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.931-935
Dokuz Eylül Üniversitesi Adresli: Hayır

Özet

The goal of this study was to determine the role of lipooligosaccharide in the attachment of Moraxella catarrhalis to human pharyngeal epithelial cells. Strain 2951 and its P-k mutant strain 2951 galE were used in this study. This study suggests that the p(k) epitope of LOS is not an adhesin for M. catarrhalis, but plays a crucial role by its surface charge in the initial stage of attachment.