The prevalence and clinical characteristics of nonradiographic axial spondyloarthritis among patients with inflammatory back pain in rheumatology practices: a multinational, multicenter study


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Burgos-Varga R., Wei J. C., Rahman M. U., Akkoc N., Haq S. A., Hammoudeh M., ...More

ARTHRITIS RESEARCH & THERAPY, vol.18, 2016 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 18
  • Publication Date: 2016
  • Doi Number: 10.1186/s13075-016-1027-9
  • Journal Name: ARTHRITIS RESEARCH & THERAPY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Keywords: Nonradiographic axial SpA, Ankylosing spondylitis, Prevalence, Inflammatory low back pain, Chronic low back pain, PLACEBO-CONTROLLED TRIAL, SOCIETY CLASSIFICATION CRITERIA, ANKYLOSING-SPONDYLITIS, RADIOGRAPHIC SACROILIITIS, FOLLOW-UP, EFFICACY, DISEASE, SAFETY, COHORT
  • Dokuz Eylül University Affiliated: Yes

Abstract

Background: Patients with ankylosing spondylitis (AS), who by definition have radiographic sacroiliitis, typically experience symptoms for a decade or more before being diagnosed. Yet, even patients without radiographic sacroiliitis (i.e., nonradiographic axial spondyloarthritis [nr-axSpA]) report a significant disease burden. The primary objective of this study was to estimate the prevalence and clinical characteristics of nr-axSpA among patients with inflammatory back pain (IBP) in rheumatology clinics in a number of countries across the world. A secondary objective was to estimate the prevalence of IBP among patients with chronic low back pain (CLBP).