BODIPY-Au(I): A Photosensitizer for Singlet Oxygen Generation and Photodynamic Therapy

ÜÇÜNCÜ M., Karakus E., Demirci E. K., Sayar M., Dartar S., Emrullahoglu M.

ORGANIC LETTERS, cilt.19, sa.10, ss.2522-2525, 2017 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 19 Sayı: 10
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1021/acs.orglett.7b00791
  • Dergi Adı: ORGANIC LETTERS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.2522-2525
  • Dokuz Eylül Üniversitesi Adresli: Hayır

Özet

Upon complexation with Au(I), a photoinactive BODIPY derivative was transformed into a highly photoactive triplet sensitizer. Along with high efficiency in singlet oxygen generation (Phi(Delta) = 0.84), the new BODIPY Au(I) skeleton showed excellent photocytotoxic activity against cancer cell lines (EC50 = 2.5 nM).