BODIPY-Au(I): A Photosensitizer for Singlet Oxygen Generation and Photodynamic Therapy

ÜÇÜNCÜ M., Karakus E., Demirci E. K., Sayar M., Dartar S., Emrullahoglu M.

ORGANIC LETTERS, vol.19, no.10, pp.2522-2525, 2017 (SCI-Expanded, Scopus) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 19 Issue: 10
  • Publication Date: 2017
  • Doi Number: 10.1021/acs.orglett.7b00791
  • Journal Name: ORGANIC LETTERS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.2522-2525
  • Dokuz Eylül University Affiliated: No

Abstract

Upon complexation with Au(I), a photoinactive BODIPY derivative was transformed into a highly photoactive triplet sensitizer. Along with high efficiency in singlet oxygen generation (Phi(Delta) = 0.84), the new BODIPY Au(I) skeleton showed excellent photocytotoxic activity against cancer cell lines (EC50 = 2.5 nM).