Screening of Australian Plants for Antimicrobial Activity against Campylobacter jejuni

Kurekci C., Bishop-Hurley S. L., Vercoe P. E., Durmic Z., Al Jassim R. A. M., McSweeney C. S.

PHYTOTHERAPY RESEARCH, cilt.26, sa.2, ss.186-190, 2012 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 26 Sayı: 2
  • Basım Tarihi: 2012
  • Doi Numarası: 10.1002/ptr.3526
  • Dergi Adı: PHYTOTHERAPY RESEARCH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.186-190
  • Anahtar Kelimeler: Campylobacter jejuni, antimicrobial activity, Australian plant extracts, minimal inhibitory concentration
  • Dokuz Eylül Üniversitesi Adresli: Hayır

Özet

Campylobacter jejuni is the most common cause of acute enteritis in humans, with symptoms such as diarrhoea, fever and abdominal cramps. In this study, 115 extracts from 109 Australian plant species were investigated for their antimicrobial activities against two C. jejuni strains using an in vitro broth microdilution assay. Among the plants tested, 107 (93%) extracts showed activity at a concentration between 32 and 1024 mu g/mL against at least one C. jejuni strain. Seventeen plant extracts were selected for further testing against another six C. jejuni strains, as well as Campylobacter coli, Escherichia coli, Salmonella typhimurium, Bacillus cereus, Proteus mirabilis and Enterococcus faecalis. The extract from Eucalyptus occidentalis demonstrated the highest antimicrobial activity, with an inhibitory concentration of 32 mu g/mL against C. jejuni and B. cereus. This study has shown that extracts of selected Australian plants possess antimicrobial activity against C. jejuni and thus may have application in the control of this organism in live poultry and retail poultry products. Copyright (C) 2011 John Wiley & Sons, Ltd.