Phenotype properties and status of corticosteroid resistance among patients with uncontrolled asthma.

Çımrın A. H., Akpinar B., Tertemiz K. C., Omeroglu G., Alpaydin A., Ellidokuz H., ...Daha Fazla

Allergologia et immunopathologia, cilt.41, sa.5, ss.304-9, 2013 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 41 Sayı: 5
  • Basım Tarihi: 2013
  • Doi Numarası: 10.1016/j.aller.2012.04.009
  • Dergi Adı: Allergologia et immunopathologia
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.304-9
  • Anahtar Kelimeler: Glucocorticoid lymphocyte proliferation suppression test, Glucocorticoid resistance, Severe asthma, Asthma phenotype, Uncontrolled asthma, LYMPHOCYTE-T ACTIVATION, GLUCOCORTICOID RESISTANCE, DISEASE SEVERITY, CELLS, PROLIFERATION, CYCLOSPORINE
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Background: Control cannot be achieved in some asthmatics although optimal monitoring and treatment is administered. Glucocorticoid (GC) resistance is one of the reasons of poor asthma control. We aimed to investigate GC resistance by lymphocyte proliferation suppression test (LPST) in uncontrolled asthmatics.