Tissue Engineering of 3D Organotypic Microtissues by Acoustic Assembly

Zhu Y., Serpooshan V., Wu S., Demirci U., Chen P., GÜVEN S.

ORGANOIDS, cilt.1576, ss.301-312, 2019 (SCI-Expanded, Scopus) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 1576
  • Basım Tarihi: 2019
  • Doi Numarası: 10.1007/7651_2017_68
  • Dergi Adı: ORGANOIDS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.301-312
  • Anahtar Kelimeler: 3D organotypic microtissues, Acoustic assembly, Acoustic waves, Cardiac scaffold, Cardiomyocyte, Cell assembly, Cell spheroids, In vitro tissue model, Regenerative medicine, Spheroid assembly, Tissue engineering
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

There is a rapidly growing interest in generation of 3D organotypic microtissues with human physiologically relevant structure, function, and cell population in a wide range of applications including drug screening, in vitro physiological/pathological models, and regenerative medicine. Here, we provide a detailed procedure to generate structurally defined 3D organotypic microtissues from cells or cell spheroids using acoustic waves as a biocompatible and scaffold-free tissue engineering tool.